Unexplained loss of muscle mass - Rejuvenate Clinic

What is unexplained loss of muscle mass?

Unexplained loss of muscle mass, known as idiopathic atrophy, is a concerning medical condition where muscle seems to waste away for no clear reason. This inexplicable muscle wasting can occur in both men and women, though it more commonly affects men over 60 years old.

Some key things to know about idiopathic atrophy:

• Symptoms - The main symptom is gradual loss of muscle, especially in the shoulders, arms, and thighs. This leads to feelings of weakness and fatigue.
• Causes - The exact cause is unknown, hence "idiopathic." Contributing factors may include nerve damage, reduced testosterone, inflammation, inactivity, or aging.
• Diagnosis - After ruling out other causes of muscle loss, doctors can confirm a diagnosis of idiopathic atrophy through exams, lab tests, EMGs, MRIs or muscle biopsies.
• Treatments - Unfortunately, there are no highly effective treatments. Options like physical therapy, light strength training, testosterone therapy or anti-inflammatory drugs may help slow further muscle loss.

So in summary, unexplained loss of muscle mass is a complex condition without a clear origin. Doctors don't know exactly why certain people - especially older men - gradually lose muscle strength and mass. Contributing factors may include aging, hormones, nerve issues or inflammation. Diagnosis involves many tests to rule out other causes. And while bothersome, the condition is not immediately life-threatening. Treatment aims to slow further muscle wasting to preserve strength and function.

If you have any other questions about this topic of mysterious muscle loss, feel free to ask.